HMX Pro Genetics
Genetics – Essentials
Get essential genetics knowledge to prepare for the future of health care.
The way we diagnose and treat diseases is changing, with new technologies enabled by a deeper understanding of the human genome and its relationship to health and disease. This shift has broad implications for those who work in health care and related areas.
HMX Pro Genetics – Essentials covers the basic concepts required to understand the field of genetics today, with an emphasis on explaining how variation in DNA sequence occurs, is inherited, and can lead to disease.
This foundational course prepares participants for more in-depth investigation of how genetics is changing health care, including advanced topics like cancer genomics and precision oncology and genetic testing and sequencing technologies.
Overview of Genetics and Genomics
- Introduction to the Genomic Revolution
- The Human Genome
The Central Dogma and Genetic Variation
- Representations of DNA
- Central Dogma Overview
- The Central Dogma and Genetic Variation
Mendelian Inheritance of Disease
- Meiosis and Inheritance
- Autosomal Inheritance
- Sex-linked Inheritance
- Mitochondrial Inheritance
- Pedigree Analysis
- Penetrance and Expressivity
Genetic Variation and Architecture
- Genetic Variation and Architecture
- Whole Chromosome Aneuploidy
- Structural Variation
- Unstable Repeats
- Common Complex Traits
- Genetic Testing
- The Promise of Genetics in Human Health and Disease
Christine DeGennaro, PhD
Lecturer in Genetics, Harvard Medical School
Robert C. Green, MD, MPH
Professor of Medicine, Harvard Medical School
Associate Physician, Brigham and Women’s Hospital
Geneticist, Brigham and Women’s Hospital
Director, Genomes2People Research Program at Brigham and Women’s Hospital
Carrie Blout, MS, CGC, LGC
Senior Genetic Counselor, Brigham & Women’s Hospital
Frequently asked questions
Who should take this course?
This course is designed for professionals in health care, life sciences, and related industries who want to have a better understanding of key genetics concepts for their work.
Note: We also offer HMX Fundamentals Genetics for those seeking a broader overview of the field; we recommend reviewing topic outlines and choosing the most appropriate course for your needs. It is not recommended to take both courses as there is some overlap in topics. The Essentials course is designed specifically for professional learners, and is focused on the key knowledge needed to succeed in the advanced HMX Pro courses.
What do participants need to know to succeed in this course?
We recommend knowledge of basic chemistry, biology, and physics – no advanced knowledge is required.
What is the time commitment?
Most people can expect to spend around 10–20 hours total, but this depends on your baseline knowledge, how carefully you take notes, and how seriously you take the assessments. Lessons from the courses are released weekly and remain available until the courses end, so you can work at your own pace. There is a final exam at the end of each course that can be taken any time during the final exam period.
Can participants earn certificates from Harvard Medical School?
There are two certification levels, based on participant scores:
- Certificate of Achievement
- Certificate of Completion
What Learners Say
“It was amazing the way all the animations were conducted, and how they show concepts in a very basic, nice way.”
“There was a very good arrangement of the lessons; the structure of the course was very good.”